1/2
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Biological introduction, neurons, ion pumps, ion channels, spikes, synapses.
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D&A pp5-7, note 3/5.
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3
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Background: pictures from the web and videos from youtube.
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See Gallery
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4/5
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Synapses, different synapses, inhibition and excitation. Recap of Boltzmann's law, typical voltage, capacitance, resistance and the typical sub-threshold timescale. Start of equilibrium potential.
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D&A s5.2
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6
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Background: guest lecture by Hugh Garavan from TCIN/Psychology about neuroimaging and neurobiology.
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Hugh Garavan
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7/8
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Equilibrium equation and the Nearst equation, the leak current, the potassium and sodium currents, persistient and transient gates, the equations for n, m and h. The Hodgkin-Huxley equation. Informal class survey.
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D&A ss5.2/5.5/5.6, note 4.
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9
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Reponse to class survey. Graphs of n, m and h and of HH spikes.
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Notes 1/2
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10/11
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Bank holiday.
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12
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Mention of the cable equations. Integrate and Fire neurons.
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D&A s6.3 (cables) and s5.4 (I&F)
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13/14
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More integrate and fire neurons, refactory currents. Modelling synapses.
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D&A s5.4 and s5.8, note 6.
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15
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Modelling synapses.
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D&A s5.8
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16/17
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Cancelled because of SFI summit
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18
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Problem sheet 1 solutions.
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PS1
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19/20
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Introduction to the decoding section; S->stuff->R, some examples. Start of a discussion of firing rates.
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Pillow Et Al (2008). D&A s1.2, first page or so.
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21/22/23
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More on firing rates: smoothing with a kernel. Tuning curves. Weber's law. Spike Triggered Average.
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D\&A ss2.1/2.2 and D\&A 1.3
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24
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Start of the linear model.
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D\&A s2.4
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25/26
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The linear model; introduction, relationship to the the Voltera expansion. Calculation of the kernel. Reverse correllation. Relationship with correllations.
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D\&A ss2.4/2.9A
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27
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Background discussion: auditory processing in zebra finch.
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Sen Et Al (2001), Theunissen Et Al (2000).
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28/29
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The Poisson distribution: homogeneous case. Fano factor. Inhomogeneous Poisson process. Start of plasticity.
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D\&A s1.4
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30
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Problem sheet 2 solutions.
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PS2
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31/32
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Plasticity, Hebbs rule, rate based examples. Spike Timing dependent plasticity.
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D\&A ss8.1/8.2 pp291/292
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33
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Guest lecture by Richard Reilly.
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Richard Reilly
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