Electronic Journal of Differential Equations, Vol. 2019 (2019), No. 92, pp. 1-13. Title: Periodic solutions for seasonal SIQRS models with nonlinear infection terms Authors: Shaday Guerrero-Flores (Univ. Michoacana, Morelia, Mich., Mexico) Osvaldo Osuna (Univ. Michoacana, Morelia, Mich., Mexico) Cruz Vargas-de-Leon (Inst. Politecnico Nacional, C. Mexico, Mexico) Abstract: In this work, we considered a family of SIRS models for a fatal disease, with seasonal variation in the contact rate and isolation control strategies. We establish the existence of periodic orbits of seasonal SIQRS disease, by using Leray-Schauder degree theory. Examples related to the seasonal variation in respiratory syncytial virus infection are included. Submitted April 25, 2018. Published July 24, 2019. Math Subject Classifications: 37J45, 34C25, 92D30, 34D23. Key Words: Leray-Schauder degree; SIQRS models; periodic orbits.